By Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson
Anesthesia and Analgesia in Laboratory Animals focuses fullyyt at the distinct anesthetic, analgesic, and postoperative care necessities linked to experimental surgical procedure. backed by means of the yankee university of Laboratory Animal medication, this informative paintings presents the reader with brokers, equipment, and methods for anesthesia and analgesia that ascertain humane and winning procedural results. Key positive aspects * specializes in a wide selection of animal species utilized in examine * presents a entire assessment of the pharmacology of anesthetics and analgesics * comprises tracking of analgesia and anesthesia * Organizes issues through species for brokers and techniques of offering anesthesia, analgesia, and post-op care to animals * No different American textual content is dedicated totally to this subject
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Extra resources for Anesthesia and Analgesia in Laboratory Animals
Nonflammable and nonexplosive: It should be nonflammable when mixed with air, oxygen, or nitrous oxide. 3. High potency: It should be easily delivered so that high concentrations of oxygen can be administered during anesthesia. 4. Low solubility in blood: Blood/gas solubility should be low in order that induction and emergence from anesthesia are rapid. This enables rapid and precise control of anesthetic depth. 5. Nonirritating: It should not cause irritation to the respiratory system, bronchospasm, or breath-holding.
Likewise, factors that decrease ventilation slow the equilibration time. Uptake of anesthetic into blood and tissue opposes or limits the rise in alveolar concentration. The greater the uptake, the lower the alveolar concentration will be relative to the inspired concentration. Anesthetics with high blood or tissue solubilities (see Section II,D) thus take longer for the alveolar concentration to increase to that required for anesthesia. Conditions that increase cardiac output increase the quantity of blood passing the alveolar membrane per unit time.
IV. U p t a k e , Distribution, and E l i m i n a t i o n V. I n h a l e d A n e s t h e t i c s A. N i t r o u s O x i d e B. E t h e r . . . . . . . . . . . . . . . . . . . . . . . . III. M o d e of A c t i o n . . . . . . . . . 33 33 35 35 36 . . . . . . . . . . . . . 36 . . . . . . . . . . . . . . 36 . . . . . . . . . . . . . . . . C. M e t h o x y f l u r a n e 29 30 . . . . . . . . . . . .
Anesthesia and Analgesia in Laboratory Animals by Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson